Skip to main content

Immuno-oncology: Combination Therapies and Emerging Targets

 

The study of and creation of therapies that use the immune system of the body to combat cancer are known as immuno-oncology. Our immune system, which is made up of a complex web of organs, cells, and molecules, guards us against external invaders like bacteria, fungus, and viruses that might infect us. The immune system is capable of locating and eliminating foreign objects as well as attacking aberrant cells.

The immune system has the best chance of specifically destroying tumours without harming healthy tissue and having long-term memory that can stop cancer from coming back. The development of tumours can be permanently prevented or managed by a mechanism known as immunosurveillance, according to research in immuno-oncology conducted over the past 30 years. Recognition of tumour antigens is what gives the immune response its tumour specificity.

The most well-established therapeutic class of IO drugs to date, immune checkpoint inhibitors have demonstrated significant efficacy in treating a variety of cancers. For the treatment of non-small-cell lung carcinoma, gastric cancer, head and neck squamous cell carcinoma, and cervical cancer with pembrolizumab (Keytruda, Merck), as well as for the treatment of urothelial carcinoma with atezolizumab (Tecentriq, Roche), biomarker testing for the programmed death-ligand 1 (PD-L1) checkpoint target has been developed and is now required.

Labels:

Comments

Post a Comment

Popular posts from this blog

The Global Autoclave Equipment Market Continues To Grow Owing To the Rising Demand from Healthcare Sectors for Sterilizing Medical Equipment to Ensure the Safety of the Post-Surgical Period

  Autoclave equipment is the most popular sterilization method in the industry and is used for many applications including the manufacture of food products. It is widely used in the foodservice industry to sterilize and cleanse equipment used in the process of preparing and serving food. The autoclave is the abbreviated form of autolysis which means oxidation. Autoclaves have various parts including an electric motor, a condenser, and a burner. Autoclave equipment includes vials for sealing the autoclave, a glass or plastic container that has been lined with wax or plastic, and the appropriate autoclave equipment accessories such thermometer for measuring the temperature of the autoclave. All modern steam sterilizing equipment & autoclave machines provide a much-refined workflow experience, which makes you reconsider whether or not steam sterilizing is all it can be. A wide range of sterilization methods is used for sterilizing your medical and laboratory specimen so the right ...
Post a Comment
Read more

Biologics Market Increasing Prevalence of Chronic Diseases to Augment Growth of the market

  A  biologic  drug ( biologics ) is a product that is produced from living organisms or contains components of living organisms.  Biologic  drugs are widely used to prevent, diagnose, treat, or cure a variety of diseases, including infectious diseases, autoimmune disorders, chronic kidney disease, and cancer. Market Dynamics In the recent past, several novel biopharmaceutical products were approved by major regulatory bodies and major players in the market have launched various novel and innovative biopharmaceutical products. Rapid approvals and launches of novel products in the market are expected to be major drivers for growth of the biologicsmarket . 
Post a Comment
Read more

Treprostinil Drugs Market - High Prevalence of Pulmonary Arterial Hypertension and R&D of New Formulations of Treprostinil to Augment Growth of market

  Treprostinil is an antihypertensive agent used to treat patients with pulmonary arterial hypertension. It can also be used in the treatment of Degos disease, an extremely rare disorder in which small and medium sized arteries become blocked (occlusive arteriopathy), restricting the flow of blood to affected areas. Market Dynamics High prevalence of pulmonary arterial hypertension is expected to propel growth of the treprostinil drugs market . For instance, according to the study, ‘High Geographic Prevalence of Pulmonary Artery Hypertension: Associations with Ethnicity, Drug Use, and Altitude’, published in February 2020, in the journal Pulmonary Circulation, the overall pulmonary arterial hypertension incidence was 14 cases per million and the annual period prevalence of pulmonary arterial hypertension was 93 cases per million. Decline in new prescriptions for treprostinil-based products is expected to hinder growth of the treprostinil drugs market. For instance, United The...
Post a Comment
Read more