Skip to main content

Immuno-oncology: Combination Therapies and Emerging Targets

 

The study of and creation of therapies that use the immune system of the body to combat cancer are known as immuno-oncology. Our immune system, which is made up of a complex web of organs, cells, and molecules, guards us against external invaders like bacteria, fungus, and viruses that might infect us. The immune system is capable of locating and eliminating foreign objects as well as attacking aberrant cells.

The immune system has the best chance of specifically destroying tumours without harming healthy tissue and having long-term memory that can stop cancer from coming back. The development of tumours can be permanently prevented or managed by a mechanism known as immunosurveillance, according to research in immuno-oncology conducted over the past 30 years. Recognition of tumour antigens is what gives the immune response its tumour specificity.

The most well-established therapeutic class of IO drugs to date, immune checkpoint inhibitors have demonstrated significant efficacy in treating a variety of cancers. For the treatment of non-small-cell lung carcinoma, gastric cancer, head and neck squamous cell carcinoma, and cervical cancer with pembrolizumab (Keytruda, Merck), as well as for the treatment of urothelial carcinoma with atezolizumab (Tecentriq, Roche), biomarker testing for the programmed death-ligand 1 (PD-L1) checkpoint target has been developed and is now required.

Comments

Popular posts from this blog

Autologous Stem Cell and Non-Stem Cell Based Therapies Market Analysis

  A primary driver for this market is the worldwide increase in occurrence of diabetes and cancer, across all age groups. According to the World Health Organization (WHO) 2018 statistics, the number of people with diabetes has risen from 108 million in 1980 to 422 million in 2014. Moreover according to the World Health Organization cancer factsheet 2018, Cancer is the second leading cause of death globally, and is responsible for an estimated 9.6 million deaths in 2018.  Furthermore, increasing old age population is another driver, which is anticipated to create a high growth scenario for the market. As per the World Population Prospects 2019 revision, the number of people aged 80 years or over is projected to be triple, from 143 million in 2019 to 426 million in 2050. Alternatively, factors restraining the market are complications and risks associated with the treatment including diarrhea, nausea, hair loss, vomiting, severe infections, infertility, and heart complications....

North America is expected to lead the global cosmetology market due to growing number of minimally invasive surgeries in the region

  Market Overview: Cosmetology is the field of a beauty practice that includes a variety of practices aimed at making individual’s look and feel their best. Competitive Landscape: GC Aesthetics, Mentor Worldwide LLC, Sientra Inc., Zimmer Holdings Inc., 3M Health Care, Allergan, Inc., Implantech Associates Inc., Institut Straumann AG, Nobel Biocare Holding AG, and Spectrum Designs Medical.   Key Market Drivers: An increasing number of cosmetic surgeries is expected to expand the global cosmetology market size. For instance, according to American Society of Plastic Surgeons (ASPS) 2017 reports, around 17.5 million cosmetic surgeries were performed in 2017, U.S. among which breast augmentation, liposuction, and nose reshaping were the top three procedures. High preferences for Botox surgeries which are used to reduce wrinkles and maintain youthful skin is again fostering the growth of the market growth. According to the same source, around 65% of women prefer Botul...

Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers Market is Expected to Grow Drastically, Assured By Experts From 2023 To 2028

  Surgical hemostat is a surgical tool used in many surgical procedures to control bleeding. Surgical hemostats covered in this report include thrombin-based, combination hemostats, oxidized regenerated cellulose-based, gelatin-based, and collagen-based. Internal tissue sealants are typically used in surgeries to bind or hold internal tissues such as blood vessels, internal organs, bone cartilage, dura matter and others. The global surgical hemostats, internal tissue sealants and adhesion barriers market is estimated to account for US$ 4,231.4 Mn in terms of value in 2020 and is expected to reach US$ 7,346.7 Mn by the end of 2027 Global Surgical Hemostats, Internal Tissue Sealants and Adhesion Barriers Market: Drivers Increasing number of surgical procedures is expected to propel growth of the global surgical  hemostats , internal tissue sealants and adhesion barriers market over the forecast period. For instance, according to ‘Surgical operations and procedures sta...