The immune
system produces antibodies in response to pathogen invasion. Antigens are the
collective term for the invasive bacteria, viruses, or other foreign molecules.
Antibodies are proteins, or polypeptides which have specific antigen
recognition sites. It is possible to have antibodies made using custom antibody
production when an antibody is required against a particular antigen but it is
not offered by a supplier. These antibodies can be either polyclonal or
monoclonal, depending on how they are produced and harvested. Polyclonal antibodies are
capable of recognizing multiple sites on an antigen. They are derived from
different B-cell lineages. Monoclonal antibodies recognize only one epitope or
site on an antigen, and are derived from a single B-cell line.
Global custom antibody service
market is estimated to be valued at US$
444.85 Million in 2022 and expected to reach US$ 930.46 million by 2030, witnessing
a CAGR of 9.7 % over
the forecast period (2022-2030).
Market players are indulged in launching customized services for the
development of custom antibodies that are used for research purposes, and this
is expected to create lucrative growth opportunities in the custom antibody
service market
The increase in organic strategies like new customized service launch is
expected to drive the growth the market. For instance, in November 2020,
AMSBIO, a leading provider of quality life science research reagents and
services, announced the launch of development services for rabbit and mouse
recombinant monoclonal antibodies. The DimAb development platform, a technology
revolution for monoclonal antibody development, which differs from traditional
hybridoma fusion methods, is the foundation for the creation of recombinant
monoclonal antibodies. It can extract IgG genes from B cells of animals that
have received an immunization. These antibodies aid in the creation and
marketability of pharmaceuticals.
Global Custom Antibody Service Market: Restraint
Challenges involved in the production of customized antibodies is the
major factor hampering the growth of the custom
antibody services market. Some challenges includes:
·
Low yield: In vitro production cultures often yield less antibody/ml
than in vivo ascitic fluid method
·
Cell death: Maintaining optimal cell growth and viability is essential
for high antibody yields and an optimized process
·
Contamination: In vitro production cultures are subject to risks of
contamination associated with long-term cell cultures
·
Time-consuming: In vitro production cultures often have to be maintained
over a long period of time in order to yield desired quantities of antibodies
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