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B-cell Maturation Antigen (BCMA) Targeted Therapies Market Development Analysis Contributing Top Vendor Landscape and Economic Growth 2028

 


BCMA is a member of tumor necrosis factor family and has critical role in the regulating B-cell proliferation and survival. The interaction of BCMA with its ligand has also shown to promote the progression of cancer. Further, studies have also demonstrated that BCMA is central to the survival of multiple myeloma cells. Therefore, researchers have adopted several approaches to target this antigen as an alternative for the management of multiple myeloma.

Drivers:

Increasing number of recurring cases of MM across the world is expected to augment growth of the global B-cell maturationAntigen (BCMA) targeted therapies market during the forecast period. Patients undergoing radiation therapy and chemotherapy are at higher risk of cancer recurrence because they develop resistance to these therapy. At this time, there is no cure for recurrent cancer and therefore BCMA targeted therapies provide successful therapeutic options for the treatment of recurrent MM.

Increasing number of pipeline products is expected to boost growth of the B-cell maturation Antigen (BCMA) targeted therapies market

Market players are actively investing in research and development of novel multiple myeloma therapies. These therapies include chimeric antigen receptor T cells, antibody-drug conjugate, and Bi-specific antibodies. For instance, GlaxoSmithKline Plc. (GSK2857916) is developing the antibody drug conjugate drug for relapsed/refractory multiple myeloma and other advanced hematologic malignancies expressing BCMA. The robust pipeline of therapies for the treatment of multiple myeloma is expected to boost growth of the B-cell maturation Antigen (BCMA) targeted therapies market.

Market Dynamics

Increasing prevalence of multiple myeloma is expected to favor the B-cell maturation antigen (BCMA) targeted therapies market worldwide. According to the American Cancer Society, U.S., in 2016, the lifetime risk for multiple myeloma was around 1 in 143 people, with an estimated 30,280 adults (17,490 men and 12,790 women) diagnosed with multiple myeloma. The mortality rate of the disease was estimated to be 12,590 (6,660 men and 5,930 women) in 2016. Key players are actively involved in the development of immunotherapies targeting BCMA for the treatment of multiple myeloma, the demand for which is expected to increase, This in turn, is expected to boost development of novel treatments for relapsed or refractory myeloma. Furthermore, patients undergoing existing drug therapies are prone to the risk of relapse. Hence, B-cell maturation antigen targeted therapy, which primarily addresses this concern is expected to gain rapid traction.

 

 

 

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